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150 Contemporary Topics and Careers in the Veterinary Sciences
Designed to expose students to topics of importance to the animal health
field as well as introduce them to the academic and professional options they
will face as undergraduates, Aiken, Fall
299 Independent Student
301 Physiology of Domestic and Laboratory Animals
Form and function of the major organs and systems of farm animals, Hellekant,
Fall (crosslisted with MAS 301)
350 Parasitology
General Biology, ecology and phylogeny of animal parasites, including those of
humans; host-parasite interactions; general epidemiological principles of parasitic
infections, Christensen, Spring (crosslisted with Med Micro and Zoology 350)
351 Parasitology Laboratory
Optional laboratory component of Zoology/Med Micro 350. Emphasis on experiments
involving live animal parasites, including: trematodes, tapeworms, gapeworms,
hookworm, ascarids, trichina, filaria, trypanosomes, coccidia and malaria, Christensen,
Spring (crosslisted with Med Micro and Zoology 351)
370 Livestock Production and Health in Agricultural Development
Physical, biological and social nature of animal agriculture systems and their
improvement in developing countries; analysis of the state of livestock research
and development in the developing countries and the world role of US animal agriculture
(crosslisted with MAS, Dy Sci and Poul Sci 370)
371 Medical Entomology
Arthropods of medical and veterinary importance, how they affect their hosts
and transmit diseases (crosslisted with Entom and Zoology 371)
375 Special Topics: Computer Sequence Analysis
Undergraduate level hands-on introductory laboratory course for aspiring molecular
biologists and genetic engineers, designed to acquaint students with fundamental
computerbased methods used to answer basic research questions about genetic
sequence information, protein structure and elementary genetic engineering. The
course assumes a working knowledge of DNA, RNA, protein and cell biology concepts,
and introduces students to commonly used software packages for genetic analysis
of nucleic acid and protein sequences. Topics will include: overview of UNIX
including file and directory management; introduction to sequence analysis; genetics
computing; restriction analysis: protein translation; the genetic code; database
searching; comparison methods; sequence alignments; pattern recognition; phylogenetic
reconstruction; bibliographic information retrieval. LAB FORMAT: The first
hour of each 2 hr laboratory is lecture/demonstrations by the instructor on the
fundamental concepts of molecular biology and computer science that underpin
the laboratory exercises. The second hour is handson computer exercises
by students from a laboratory manual written by the instructor. Lab is graded
on class participation, computer-based homework assignments, and in-class exams/quizzes.
Palmenberg, Fall/Even
399 Coordinative Internship/Cooperative Education
500 Molecular Biology Techniques
The objective of the course is to familiarize students with recombinant DNA technology.
This will be accomplished through lectures as well as hands on exposure to
methodologies
used in molecular biology laboratories, Aiken, Spring
528 Immunology
Development and functions of immune response in animals; a comprehensive
study of experimental humoral and cellular immunity, Splitter, Fall (crosslisted
with
Bact, Med Micr 528)
529 Immunology Laboratory
Selected techniques illustrating concepts of cellular and humoral immunity as
a supplement to Immunology 528 (crosslisted with Med Micr 529)
548 Diseases of Wildlife
Occurrence, principles, concepts and significance of disease in wildlife, Fall/Even
(crosslisted Wl Ecol 548)
606 Colloquium in Environmental Toxicology
Lectures by resident and visiting professors on toxicology and problems related
to biologically active substances in the environment (crosslisted with Env Tox,
Entom, Pl Path, Soil Sci, and Wl Ecol 606)
625 Toxicology I
Basic principles of toxicology and biochemical mechanisms of toxicity in mammalian
species and man. Correlation between morphological and functional changes caused
by toxicants in different organs of the body (crosslisted with Env Tox, Medicine,
Oncology, Path, Phmcol-P, Phmcol-M, and Prev Med 626)
626 Toxicology II
A course surveying the basic methods and fundamental biochemical mechanisms of
toxicity. Toxicity in mammalian organ systems, techniques for evaluating toxicity,
as well as mechanisms of species specificity, and environmental interactions
(with toxicant examples) are presented (crosslisted with Env Tox, Medicine, Path,
Phmcol-P, Phmcol-M, and Prev Med 626)
660
Electron Microscopy: Theory and Practice
A practical course for graduate students in biological and biological-related
areas (bioengineering, biomaterials, etc.) Covers basic theory and technology
used for preparation, labeling, observation, and analysis of a wide variety of
biological and biomaterial specimens. Covered are SEM, TEM, EF-TEM, HVEM, SFM,
image processing and a number of EM and LM-EM correlative procedures, Albrecht,
Proctor, Summer/Even (crosslisted with Anatomy 660)
681 Senior Honors Thesis
699 Special Problems
700 Topics in Toxicology: Immunotoxicology
Considers effects and potential effects of toxicants on the immune system at
both the basic and applied level, Jefcoate/Albrecht, I, II, SS (listed as Env
Tox 700)
701 Experimental Surgery and Techniques in Research Animals
Lab taught twice weekly for the first 8 weeks. For non-professional graduate
students in the biological sciences. Techniques in anesthesia and experimental
surgery on research animals including rats, guinea pigs, rabbits, dogs, pigs,
and ruminants, Bjorling, Jarvis, Spring
720 Topics in Immunology
(crosslisted with Med Micr 720)
740 Mechanisms in Microbial Pathogenesis
Host-pathogen relationships in microbial diseases. Entry level course for infectious
diseases sequence (crosslisted with Med Micr, Bact 740)
750 Host-Parasite Relationships in Vertebrate Viral Disease
Detailed study of the pathogenesis of vertebrate viral disease, stressing viral
invasion, dissemination, mechanisms of disease production and resistance, and
transmission, Brandt, Spring/Even
760 Molecular Genetics of Microbial Pathogenesis
The genetics and biochemistry of host cell adherence, cellular invasion and immune
evasion by different human and animal microbial pathogens. The mechanisms and
regulation of adhesins, toxins and antigenic variation (crosslisted with Med
Micr, Bact 760)
790 Immunology of Infectious Diseases
Immunobiology and immunogenetics of resistance to infectious disease agents of
man and animals; immunoregulatory mechanisms associated with evasion of host
immunity, Mansfield, Spring/Odd (crosslisted with Med Micr 790)
799 Practicum in Veterinary Science Teaching
Instructional orientation to teaching at the higher education level in the agricultural
and life sciences, direct teaching experience under faculty supervision, experience
in testing and evaluation of students and the analysis of teaching performance
875 Special Topics:
Sequence Analysis and Molecular
Evolution
Graduate level course for aspiring molecular biologists and genetic engineers,
designed to answer the questions; "What can you do with your sequence once
you have it?" and "How can you put this information into realistic
biological perspective?" Topics (partial listing) includes overviews of:
RNA, DNA and protein structure; mechanisms of genetic change; sequence generation
methods; comparison and alignment algorithms; motif recognition; 2D predictions;
phylogeny calculations; database searching; discriminating coding criteria; phenotypic
selection; phylogenic reconstruction; and other exciting stuff. Prerequisites:
(a) graduate status, (b) Genetics 466 or Biochemistry 501 or equivalent. Course
is graded on class participation, in-class quizzes and exams, and written reports
on outside reading topics, Palmenberg, Fall/Odd
Sequence Analysis and Bioinformatics
Graduate level, hands-on laboratory course, taught at actual computer terminals,
designed to complement and reinforce the sequence analysis concepts presented
in the above-listed didactic course. Topics will include: overview of UNIX including
file and directory management; introduction to sequence analysis; database searching;
comparison methods; alignments; profiles and profile searching; pattern recognition;
phylogenetic reconstruction; bibliographic information retrieval. Non-negotiable
prerequisite: concurrent or previous registration in Sequence Analysis and Molecular
Evolution 875 (above). Lab is graded on class participation, computer-based
homework assignments, and in-class exams/quizzes, Palmenberg, Fall/Odd
Experimental Cell Biology/Immunology
Considers different approaches to solving current questions in the area. Emphasizes
biological problem solving, experimental design, and interpretation of results,
Albrecht, Proctor, Spring/Odd
Lectures in Geographic Medicine
Guest lecturers provide a current assessment of parasitic and infectious diseases
that impact the health of human populations in the tropics, Christensen/Weidanz,
Spring/Odd
Statistical Methods in Genomics
Complete genome sequences offer unprecedented opportunities for scientific inquiry
because they contain, encrypted within millions of nucleotide base pairs, the
parts list and instruction manual for deciphering each organism. Genomics - the
very name conjures up images of masses of data - is the science of gleaning biological
insights from complete sequence analysis, comparison, and experimentation. This
course has as its mission the proper use of statistical methods to analyze whole
genomes. The uncritical use of statistics in the quest for some mythical 5% significance
level breeds poor science and wasted effort, a problem that is often compounded
geometrically in a genomic context. We will promote how to "do it right"
while vigilantly protecting against "doing it wrong". Material covered
will include the extreme value statistics that underlie sequence similarity searches,
r-scan statistics to assess the distribution of specific sequence motifs, correspondence
analysis for analyzing codon preferences, multiple comparison issues in microarray
analysis, detection of recombination and horizontal transfer events from nucleotide
base composition, and global phylogenetic inference made possible by multiple
whole genome alignment. Whenever possible, relatively straightforward statistics
such as the Poisson and chi-squared distributions are used. The dual concepts
of statistical model selection and assessment help choose a "right"
statistic, supplemented by the kind of graphical evaluations that large amounts
of data enable. Computer simulations will be emphasized to develop an intuitive
understanding of the model fitting and validation process. Computer-intensive
techniques such as the bootstrap, permutation test, and hierarchical Bayesian
methods using MCMC, will be introduced when simple parametric models are deemed
inadequate. No prior computer programming experience is required, but a comfort
level using computer software is prerequisite, Perna/Mau (crosslisted with Statistics
692)
920 Thesis Research Seminar
930 Advanced Seminar
990 Research
